Posts

Showing posts from January, 2012

GENE THERAPY

Image
                          INTRODUCTION       The ability to transfect genes into cells and to cause their expression is leading to the practical emergence of human gene therapy wherein, functionally active genes are putatively inserted into the somatic cells of a person requiring the expression of a given protein. In simple terms, gene therapy involve insertion of genetic material into a patient’s cells to make them capable of producing therapeutic protein. Gene therapy paves way to either replace the missing or defective gene at the origin or arrest undesired gene expression (viral and oncogene expression) at the origin. Gene medicines are generally based on gene expression system that contains a therapeutic gene and a delivery system. A gene delivery system controls the distribution and access of a gene expression u...